Urinary Dickkopf-related protein 3 as a novel biomarker for kidney function decline in children with Alport syndrome

CONCLUSION: Urinary DKK3 is significantly elevated in children at early stages of AS. There was a potential association between higher DKK3 levels, worsening albuminuria, and a decline in kidney function. These findings suggest that DKK3 may be a prognostic marker for predicting the risk of kidney damage in children with …