Leptospirosis, a widespread zoonotic disease caused by Leptospira spp., affects approximately 1 million people annually and causes about 58,000 deaths worldwide. This study examines the epidemiology of leptospirosis in Ukraine from 2018 to 2023, focusing on the impact of weather and geographical factors on disease transmission. Data from the Ukrainian Centre for Disease Prevention and Control, the Ukrainian Hydrometeorological Center, and the State Agency of Water Resources of Ukraine …