The clinical effectiveness of Oxiris^(®), particularly in reducing cytokines, remains uncertain due to the limited data provided. This study explored and analyzed the application value of Oxiris^(®) endotoxin adsorption technology in a large animal model. Pigs received an intravenous LPS infusion. Six animals were treated 2 h after the infusion with an Oxiris^(®) hemadsorption using a pumpless extracorporeal technique for 6 h. Five animals served as controls. Cardiocirculatory …