Fair allocation of funding in multi-centre clinical studies is challenging. Models commonly used in Germany - the case fees (βfixed-rate modelβ, FRM) and up-front staffing and consumables (βup-front allocation modelβ, UFAM) lack transparency and fail to suitably accommodate variations in centre performance. We developed a performance-based reimbursement model (PBRM) with automated calculation of conducted activities and applied it to the cohorts of the National Pandemic Cohort Network β¦