Histopathologically confirmed radiation-induced damage of the brain - an in-depth analysis of radiation parameters and spatio-temporal occurrence

CONCLUSIONS: Accelerated hyperfractionated RT can lead to RID despite computationally low EQD2(2) and BED(2) in high-grade glioma patients. The anatomical location of RID corresponded to the general tumor distribution of gliomas and metastases. The SVZ might be a particularly vulnerable …