Changes in tissue sodium concentration and sodium relaxation times during the maturation of human knee cartilage: Ex vivo ²³ Na MRI study at 10.5 T

CONCLUSION: TSC and relaxation parameters measured with ^(23) Na MRI provide noninvasive information about changes in sGAG content and collagen matrix during cartilage maturation. Cartilage TSC quantification assuming fixed relaxation may be feasible in children older than 5 …