Sufficient Cav-1 levels in the endothelium are critical for the maintenance of the neurovascular unit in the retina

CONCLUSION: Our results indicate that a sufficient Cav-1 level over 50% of its normal abundance is vital for the proper localization of VEGFR2 and VE-cadherin, likely in a complex, at the plasma membrane, which is essential for the maintenance of normal NVU in the …