Here we report a new fusion gene, STRN3-RARA, in acute promyelocytic leukemia (APL). It cooperates with UTX deficiency to drive full-blown APL in mice. While STRN3-RARA leukemia quickly relapses after ATRA treatment, they can be restrained by …
Here we report a new fusion gene, STRN3-RARA, in acute promyelocytic leukemia (APL). It cooperates with UTX deficiency to drive full-blown APL in mice. While STRN3-RARA leukemia quickly relapses after ATRA treatment, they can be restrained by …