GOLD stage-specific phenotyping of emphysema and airway disease using quantitative computed tomography

CONCLUSION: QCT parameters showed a significant increase of emphysema from GOLD 0-4 COPD. Airway changes showed a different spatial pattern with higher values of relative wall thickness in the lower lobes until GOLD 2 and subsequent lower values in GOLD3/4, whereas there were no significant differences in the upper lobes. Both, EI and WP(5-8) are independently correlated with lung function …