Genes that drive the proliferation, survival, invasion and metastasis of malignant cells have been identified for many human cancers^(1-4). Independent studies have identified cell death pathways that eliminate cells for the good of the organism^(5,6). The coexistence of cell death pathways with driver mutations suggests that the cancer driver could be rewired to activate cell death using chemical inducers of proximity (CIPs). Here we describe a new class of molecules …